Welcome! Our laboratory studies the mechanisms underlying complex neurodegenerative diseases, including Alzheimer’s Disease, Parkinson’s Disease and Frontotemporal Lobar Degeneration (FTLD). Our techniques range from cellular neurobiology to population studies and clinical trials. We’re interested in identifying new disease-related biological pathways, evaluating new experimental therapeutics, and developing new disease-specific biomarkers.
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Latest Publications
Diniz GB, Schwartz K, Erices CT, Ott SP, Griggs DJ, Mendiola JH, Sutphen CL, Beckman D, Register TC, Hof PR, Wilson EN, Morrison JH. Plasma and cerebrospinal fluid proteomics reveal distinct patterns of senescence and neuropathology in aging rhesus macaques. Geroscience. 2026 Sep 26. doi: 10.1007/s11357-026-02555-7. PMID: 42799938. [PubMed]
Butler III, R. R., Brown, M. P., Weber, A., Cary, G., Moran Losada, P., Le Guen, Y., Mendiola, J. H., Henderson, V. W., Sha, S. J., Poston, K. L., Andreasson, K. I., Carter, G., Wagner, A. D., Mormino, E. C., Wyss-Coray, T., Longo, F. M., & Wilson, E. N. (2026). Alzheimer disease blood biomarkers reveal proteomic modules of disease progression. medRxiv. https://doi.org/10.64898/2026.08.14.26360394 [DOI]
Van Meter TE, Wilson EN, Elahi F, Rissman RA, Lago AL, Faber K, Gauthreaux K, Osorio R, Perkins M, Gray N, Morris J, Liu A, Stockwell H, Kukull W, Wilson R, Wingo TS, Kanaan NM, Russ K, Wilcock D, Biber SA, Bekris LM, Karikari TK. Pre-analytical guidelines for blood and CSF Biomarkers 2025: Recommendations from the NACC ADRC Biofluid Biomarker Best Practices Workgroup. Alzheimer's & Dementia. 2026 May;22(5):e71252. doi: 10.1002/alz.71252. PMID: 42080228; PMCID: PMC13137281. [PubMed]
Bettcher BM, Ren S, Wang Y, Carlson NE, Lippitt WL, McConnell BV, Wilson EN, Shapiro ALB, Coughlan C, Carlisle TC, Unger JR, Cook GG, Bengtson K, Gorla L, Ueberheide BM, Kanshin E, Potter H, Schulz L, Frazer-Abel A, Pelak VS. Relation of blood-based inflammation conditional networks to key immune health status and Alzheimer's biomarkers in aging adults. Neurobiology of Aging. 2026 May 9;166:14-28. doi: 10.1016/j.neurobiolaging.2026.05.001. Epub ahead of print. PMID: 42139770. [PubMed]






