Wilson Research Lab

Probing Neurodegeneration Biomarkers, Mechanisms, and Risk-Resilience Factors

Welcome! Our laboratory studies the mechanisms underlying complex neurodegenerative diseases, including Alzheimer’s Disease, Parkinson’s Disease and Frontotemporal Lobar Degeneration (FTLD). Our techniques range from cellular neurobiology to population studies and clinical trials. We’re interested in identifying new disease-related biological pathways, evaluating new experimental therapeutics, and developing new disease-specific biomarkers.

News

Welcome, Tyler!
2026-09-21 00:00:28 - Welcome, Tyler!We are excited to welcome Tyler Menold to the Wilson Lab as a PhD student in Brown University’s Brown–NIH Neuroscience Graduate Partnership Program!
Welcome, Bao!
2026-08-29 17:50:38 - Welcome, Bao!We are thrilled to welcome Bao Pham to the lab! Bao is a newly admitted PhD student in the Neuroscience Graduate Program. He will be researching translational biomarkers and biosensors of neurodegenerative diseases. Welcome, Bao!
Wilson Lab Contributes to Blood and CSF Biomarker Best-Practice Guidelines
2026-05-04 18:19:02 - Wilson Lab Contributes to Blood and CSF Biomarker Best-Practice GuidelinesWe are excited to share that our lab contributed to the new “Pre-analytical guidelines for blood and CSF Biomarkers 2025: Recommendations from the NACC ADRC Biofluid Biomarker Best Practices Workgroup,” now published in Alzheimer’s & Dementia. These guidelines, updated for the first time since 2014, reflect current ADRC best practices to minimize pre-analytical variability in blood and CSF biomarker studies and to harmonize protocols across centers. Click here to read the paper.
Welcome, Nola!
2026-04-02 15:18:08 - Welcome, Nola!We are thrilled to welcome Nola Ihejirika to the lab! Nola is a Doctoral Student in Brown University's Pathobiology Program. Nola will be working on synaptic resilience in Alzheimer's disease. Welcome, Nola!
Ted Wilson appointed to named chair
2025-12-06 14:28:21 - Ted Wilson appointed to named chairTed Wilson named Provost’s Assistant Professor of Neuroimmunology and Brain Science.

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Latest Publications

Diniz GB, Schwartz K, Erices CT, Ott SP, Griggs DJ, Mendiola JH, Sutphen CL, Beckman D, Register TC, Hof PR, Wilson EN, Morrison JH. Plasma and cerebrospinal fluid proteomics reveal distinct patterns of senescence and neuropathology in aging rhesus macaques. Geroscience. 2026 Sep 26. doi: 10.1007/s11357-026-02555-7. PMID: 42799938.  [PubMed]

Butler III, R. R., Brown, M. P., Weber, A., Cary, G., Moran Losada, P., Le Guen, Y., Mendiola, J. H., Henderson, V. W., Sha, S. J., Poston, K. L., Andreasson, K. I., Carter, G., Wagner, A. D., Mormino, E. C., Wyss-Coray, T., Longo, F. M., & Wilson, E. N. (2026). Alzheimer disease blood biomarkers reveal proteomic modules of disease progression. medRxiv. https://doi.org/10.64898/2026.08.14.26360394 [DOI]

Van Meter TE, Wilson EN, Elahi F, Rissman RA, Lago AL, Faber K, Gauthreaux K, Osorio R, Perkins M, Gray N, Morris J, Liu A, Stockwell H, Kukull W, Wilson R, Wingo TS, Kanaan NM, Russ K, Wilcock D, Biber SA, Bekris LM, Karikari TK. Pre-analytical guidelines for blood and CSF Biomarkers 2025: Recommendations from the NACC ADRC Biofluid Biomarker Best Practices Workgroup. Alzheimer's & Dementia. 2026 May;22(5):e71252. doi: 10.1002/alz.71252. PMID: 42080228; PMCID: PMC13137281.  [PubMed]

Bettcher BM, Ren S, Wang Y, Carlson NE, Lippitt WL, McConnell BV, Wilson EN, Shapiro ALB, Coughlan C, Carlisle TC, Unger JR, Cook GG, Bengtson K, Gorla L, Ueberheide BM, Kanshin E, Potter H, Schulz L, Frazer-Abel A, Pelak VS. Relation of blood-based inflammation conditional networks to key immune health status and Alzheimer's biomarkers in aging adults. Neurobiology of Aging. 2026 May 9;166:14-28. doi: 10.1016/j.neurobiolaging.2026.05.001. Epub ahead of print. PMID: 42139770.  [PubMed]

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